It is usually a normal physiological phenomenon for men to have one larger testicle and one smaller testicle. Under normal circumstances, there may be slight differences between the testicles on both sides, which are mainly related to the distribution of blood vessels in the scrotum, differences in physiological and anatomical positions, or daily life habits.
Differences in testicular size are mostly normal physiological variations. The testicles on both sides are usually not completely symmetrical, and a diameter difference of 10%-15% is common. Differential contractions of the scrotal wall muscles may cause visual differences, and uneven blood flow distribution after prolonged sitting or exercise may also temporarily affect appearance. Non-pathological factors such as varicocele and hydrocele may also cause mild asymmetry, and these conditions are usually not associated with pain or functional impairment.
In a few cases, we need to be alert to pathological changes. Acute orchitis can cause unilateral significant swelling with severe pain, and epididymal tuberculosis may cause unilateral testicular sclerosis and atrophy. Testicular tumors may present as painless swelling in the early stages, and untreated cryptorchidism may affect development. Posttraumatic hematoma or torsion can cause sudden asymmetry with associated skin ecchymosis.
It is recommended to monitor testicular changes annually with self-examination, using gentle rolling between your thumb and index finger to check for texture and shape. Avoid wearing tight underwear to reduce local compression, and pay attention to scrotal heat dissipation when working in high temperature environments. If you find that the size difference intensifies in a short period of time, if an abnormal mass is touched or accompanied by a feeling of swelling, you should go to the urology department in time. Maintaining moderate exercise to promote pelvic blood circulation and eating a balanced diet can help maintain the health of the reproductive system.

Deborah 