Arabella Chemotherapy options for cervical cancer mainly include cisplatin injection, paclitaxel injection, carboplatin injection, fluorouracil injection, gemcitabine injection, etc. Specific plans need to be formulated by doctors based on the patient's condition, stage, and tolerance. Common combination plans include cisplatin + paclitaxel, carboplatin + paclitaxel, etc.
1. Cisplatin injection
Cisplatin injection is a platinum-based chemotherapy drug that inhibits tumor growth by destroying the DNA structure of cancer cells. Suitable for advanced or recurrent metastatic cervical cancer, often combined with paclitaxel. Adverse reactions such as bone marrow suppression and nephrotoxicity may occur, and blood routine and renal function need to be monitored during treatment. Adequate hydration is required before use to prevent kidney damage.
2. Paclitaxel injection
Paclitaxel injection is a microtubule stabilizer that can block mitosis of cancer cells. It is mainly used for the second-line treatment of metastatic cervical cancer or the first-line regimen combined with cisplatin. Common side effects include alopecia, peripheral neuropathy and allergic reactions, and pretreatment with dexamethasone is required before administration to reduce the risk of allergic reactions.
3. Carboplatin injection
Carboplatin injection is a second-generation platinum preparation with lower toxicity than cisplatin. It is suitable for cervical cancer patients with poor renal function or unable to tolerate cisplatin, and is often combined with paclitaxel. The main adverse reaction is thrombocytopenia, and blood pictures need to be checked regularly. Mild nausea and vomiting may occur during treatment.
4. Fluorouracil injection
Fluorouracil injection exerts anti-tumor effects by interfering with DNA synthesis and is often used in concurrent chemoradiotherapy for locally advanced cervical cancer. Major adverse reactions include oral mucositis and hand-foot syndrome. During continuous intravenous infusion, attention must be paid to vascular protection, and severe diarrhea must be treated promptly.
5. Gemcitabine injection
Gemcitabine injection is a nucleoside analogue, suitable for second-line treatment of platinum-resistant recurrent cervical cancer. Common side effects are flu-like symptoms and bone marrow suppression, and transient fever may occur after administration. The efficacy can be improved when combined with cisplatin, but the risk of cumulative pulmonary toxicity needs to be noted.
During chemotherapy for cervical cancer, you should maintain a high-protein diet such as fish, eggs, etc., and supplement vitamin B in an appropriate amount to relieve neurotoxic symptoms. Avoid strenuous exercise before and after treatment, and monitor weight changes weekly. When severe bone marrow suppression occurs, isolation and protection are required, and liver and kidney function and tumor markers must be reviewed regularly. All chemotherapy drugs must be used strictly in accordance with the doctor's instructions. Do not adjust the dosage or interrupt treatment on your own.
